Discussion of Adamantinoma
- Adamantinoma is a rare, locally aggressive lesion that is usually 3.0–15.0 cm in diameter when discovered.
- It has a strong predilection for the tibia, which is the site of involvement in 80% of cases. It has a particular propensity for the anterior tibial diaphysis.
- In adamantinoma, the patient age is usually 20–50 years.
- The male-to-female ratio is 1.3:1.
- The typical presentation is gradual onset of dull pain.
- A low-grade malignancy, adamantinoma has the ability to metastasize. Fifteen percent of patients die with metastases, commonly to the lung, bone, lymph nodes, pericardium, and liver.
- Treatment involves wide en bloc resection; the disease appears to be more aggressive when recurrent after therapy.
 Imaging Findings for Adamantinoma
- The most characteristic radiographic feature is the location: the middle anterior cortex of the tibial diaphysis.
- The epicenter is typically eccentric.
- The appearance consists of a multilocular or slightly expansile osteolytic lesion, which may be locally aggressive.
 See Also
 External Links
 References for Adamantinoma
- Scott M. Levine, Robert E. Lambiase, and Catherine N. Petchprapa. Cortical Lesions of the Tibia: Characteristic Appearances at Conventional Radiography. RadioGraphics 2003 23: 157-177.