Bladder inflammatory pseudotumor
 Discussion of Bladder inflammatory pseudotumor
- An inflammatory pseudotumor is a nonneoplastic proliferation of cells (inflammatory pseudotumor is an interesting entity that has been reported in every organ of the body).
- Patients present most commonly with an ulcerating bleeding mass, hematuria, and voiding symptoms.
- Condition is more common in adults (mean age at diagnosis reported to be 38 years)
- The lesion is locally aggressive and may mimic malignancy clinically, at cystoscopy, and at imaging.
- The pathogenesis of inflammatory pseudotumor is not clear.
- Treatment may consist of surgery, a regimen of high-dose steroids, radiation therapy, or conservative management.
- Because imaging features may overlap, it is critical that the pathologist distinguish inflammatory pseudotumor from rhabdomyosarcoma and myxoid leiomyosarcoma to prevent unnecessary radical surgery.
 Imaging Findings for Bladder inflammatory pseudotumor
- At imaging evaluation, inflammatory pseudotumor usually appears as a single bladder mass, which may be exophytic or polypoid and which may be ulcerated.
- On CT and MR images, inflammatory pseudotumors demonstrate enhancement, and at color Doppler US, these lesions may show internal vascularity.
- Enhancement may be ring like secondary to cellular periphery with a necrotic center.
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 References for Bladder inflammatory pseudotumor
- Jade J. Wong-You–Cheong, Paula J. Woodward, Maria A. Manning, and Charles J. Davis. From the Archives of the AFIP: Inflammatory and Nonneoplastic Bladder Masses: Radiologic-Pathologic Correlation. RadioGraphics 2006 26: 1847-1868.