Central neurocytoma

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[edit] Discussion of Central neurocytoma

  • Central neurocytomas constitute approximately 0.25%–0.5% of all intracranial tumors.
  • The mean age at presentation is 29 years, with a wide age range (8 days to 67 years)
  • A relatively short clinical course (mean, 3 months) is typical, with the symptoms being related to increased intracranial pressure, mental status changes, visual deficits, or hormonal changes.
  • In rare cases, these tumors may be associated with sudden death secondary to acute ventricular obstruction.


  • Gross total surgical resection is the treatment of choice and typically curative.
  • Central neurocytomas arise from the septum pellucidum or the ventricular wall.
  • Half of the cases involve the lateral ventricles near the foramen of Monro, whereas 15% are located in both the lateral and third ventricles.
  • The histologic features are strikingly similar to those of an oligodendroglioma.
  • The term central neurocytoma should be reserved for those neoplasms occurring only in the lateral and third ventricles.
  • Lesions with similar histologic characteristics that are located outside these locations should be referred to as extraventricular central neurocytoma.


[edit] Imaging Findings for Central neurocytoma

  • The typical cross-sectional imaging appearance of a central neurocytoma is a well-circumscribed, heavily lobulated, intraventricular mass with numerous intratumoral cystlike areas.
  • The mass is most commonly located in the lateral ventricle, usually in its anterior portion near the foramen of Monro.
  • A majority of cases of central neurocytoma are affiliated with hydrocephalus or monoventricular dilatation.
  • On CT images, the lesions are hyperattenuated compared with the brain parenchyma. Cystlike areas are noted in two-thirds of cases with imaging studies. Calcification is present in half of the cases.
  • Moderate enhancement is typical after the intravenous administration of contrast media on both CT and MR images.
  • On MR images, the solid portions of the tumor are hyperintense compared with the white matter with short TR and long TR pulse sequences, whereas the cystlike regions are hypointense compared with white matter with the short TR pulse sequences.


[edit] Images

Patient #1

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[edit] References for Central neurocytoma