Chondromyxoid fibroma

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[edit] Discussion of Chondromyxoid fibroma

  • Chondromyxoid fibroma is a rare, benign, cartilaginous neoplasm.
  • It typically manifests as an eccentric, lucent, metaphyseal lesion oriented along the long axis of a bone.
  • When the lesion grows large, a "cortical bite" without periostitis is characteristic.
  • Chondromyxoid fibroma affects long bones in 80% of cases, 55% of which involve the tibia and femur.
  • In the tibia, proximal metaphyseal involvement is most common.


  • Patient age is typically 20–30 years.
  • Male-to-female ratio is usually 1:1.


  • At histologic analysis, variable proportions of fibrous, chondroid, and myxoid tissue are seen.


  • Surgical resection is performed for cure. Metastases do not occur, as this is a benign process.

[edit] Imaging Findings for Chondromyxoid fibroma

[edit] Plain film

  • Lucent, well-defined, slightly expansile lesion with endosteal sclerosis; it is oriented along the long axis of the host bone.

[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References for Chondromyxoid fibroma