Discussion of Chondromyxoid fibroma
- Chondromyxoid fibroma is a rare, benign, cartilaginous neoplasm.
- It typically manifests as an eccentric, lucent, metaphyseal lesion oriented along the long axis of a bone.
- When the lesion grows large, a "cortical bite" without periostitis is characteristic.
- Chondromyxoid fibroma affects long bones in 80% of cases, 55% of which involve the tibia and femur.
- In the tibia, proximal metaphyseal involvement is most common.
- Patient age is typically 20–30 years.
- Male-to-female ratio is usually 1:1.
- At histologic analysis, variable proportions of fibrous, chondroid, and myxoid tissue are seen.
- Surgical resection is performed for cure. Metastases do not occur, as this is a benign process.
 Imaging Findings for Chondromyxoid fibroma
 Plain film
- Lucent, well-defined, slightly expansile lesion with endosteal sclerosis; it is oriented along the long axis of the host bone.
 See Also
 External Links
 References for Chondromyxoid fibroma
- Scott M. Levine, Robert E. Lambiase, and Catherine N. Petchprapa. Cortical Lesions of the Tibia: Characteristic Appearances at Conventional Radiography. RadioGraphics 2003 23: 157-177.