Fat redistribution syndrome

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[edit] Discussion

Buffalo hump
  • AKA HIV lipodystrophy syndrome
  • Significant number of AIDS patients on HAART develop characteristic changes in body fat redistribution.
  • Features include:
    • Hypertrophy in the neck fat pad (buffalo hump)
    • Increased fat in the abdominal region (protease paunch)
    • Gynecomastia
    • Loss of fat in the midface and extremities.


  • Biochemically, these patients have increased triglycerides, total cholesterol, low-density lipoprotein-cholesterol, and extremely low high-density lipoprotein-cholesterol.
  • If left untreated, these patients develop and die of complications of metabolic origin such as cardiovascular diseases or diabetes. Biochemical features manifest before the clinical pictures become apparent.

[edit] Imaging Findings

[edit] Images

Patient #1: HIV patient developed fat redistribrution syndrome while on HAART

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