Discussion of Fibromuscular dysplasia
- Fibromuscular dysplasia (FMD) is a nonatherosclerotic, noninflammatory vascular disease.
- The pathological classification scheme for fibromuscular lesions is based on the arterial layer involved — intima, media, or adventitia — in which the lesion predominates, but are not mutually exclusive. FMD has been described using the terms dyplasia, fibroplasia, fibrodysplasia, and hyperplasia.
- Intimal dysplasia
- Medial dysplasia is the most common type (85%); causes classic stenoses alternating with aneurysms. Causes "string of beads" appearance.
- Perimedial dysplasia
- Medial hyperplasia
- Adventitial (periarterial) dysplasia
- Fibromuscular dysplasia has been described in almost every arterial bed in the body.
- Renal arteries, 60%, most common site.
- ICA or Vertebral arteries, 35%.
- Iliac arteries, 3%.
- Visceral arteries, 2%.
 Fibromuscular Dysplasia of the Renal Arteries
- Renovascular fibromuscular dysplasia tends to affect women between 15 and 50 years of age.
- Renal fibromuscular dysplasia is often discovered incidentally during the investigation of another problem.
- Fibromuscular dysplasia accounts for less than 10 percent of cases of renovascular hypertension.
- Treatment: Successful angioplasty often results in a substantial and rapid reduction of both the systolic and the diastolic blood pressure.
 Imaging Findings for Fibromuscular dysplasia
- Classic "string of beads" appearance on angiogram, CTA, or MRA
 External Links
 References for Fibromuscular dysplasia
- Slovut, David P., Olin, Jeffrey W. Fibromuscular Dysplasia. N Engl J Med 2004 350: 1862-1871