Gastrointestinal amyloidosis

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[edit] Discussion of Gastrointestinal amyloidosis

  • In both primary and secondary amyloidosis, the most commonly involved organ system is the gastrointestinal system.
  • Colon is most frequently involved. The most common finding is colonic dilatation owing to adynamic ileus and more rarely bowel wall thickening.
  • Esophageal and gastric involvement usually manifests as dysmotility, wall thickening, and gastroesophageal reflux disease, results from amyloid infiltration of the muscularis and/or destruction of the Auerbach plexus.
  • Small intestine is involvement usually manifests as diffuse or nodular wall thickening.
  • Splenomegaly is the only finding associated with splenic involvement. Spontaneous splenic rupture may occur.
  • Liver is commonly involved. Diffuse infiltration is the usually image finding, woit decreased attenuation at CT and hepatomegaly.
  • Abdominal pain, malabsorption, and hemorrhage are rare complications.

[edit] Imaging Findings for Gastrointestinal amyloidosis

  • As above

[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References for Gastrointestinal amyloidosis