Discussion of Gastrointestinal amyloidosis
- In both primary and secondary amyloidosis, the most commonly involved organ system is the gastrointestinal system.
- Colon is most frequently involved. The most common finding is colonic dilatation owing to adynamic ileus and more rarely bowel wall thickening.
- Esophageal and gastric involvement usually manifests as dysmotility, wall thickening, and gastroesophageal reflux disease, results from amyloid infiltration of the muscularis and/or destruction of the Auerbach plexus.
- Small intestine is involvement usually manifests as diffuse or nodular wall thickening.
- Splenomegaly is the only finding associated with splenic involvement. Spontaneous splenic rupture may occur.
- Liver is commonly involved. Diffuse infiltration is the usually image finding, woit decreased attenuation at CT and hepatomegaly.
- Abdominal pain, malabsorption, and hemorrhage are rare complications.
 Imaging Findings for Gastrointestinal amyloidosis
- As above
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 References for Gastrointestinal amyloidosis
- Christos S. Georgiades, Edward G. Neyman, Matthew A. Barish, and Elliot K. Fishman. Amyloidosis: Review and CT Manifestations. RadioGraphics 2004 24: 405-416.