I-131

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Contents

[edit] Full name

Iodine-131

[edit] Photon energy

364 keV

[edit] Uses, dosages, and Time of Imaging

[edit] Thyroid scan

  • Adult dose: 10 microCi
  • Time of imaging: 24 hours (repeat at 48 and 72 hours for equivocal findings)

[edit] RAIU

  • Adult dose: 50 microCi
  • Time of imaging: 24 hours (repeat at 48 and 72 hours for equivocal findings)

[edit] Thyroid cancer scan

  • Adult dose: 2 - 5 mCi
  • Time of imaging: 24 hours (repeat at 48 and 72 hours for equivocal findings)

[edit] Physical half life

8.1 days

[edit] Biological half life

[edit] Normal distribution

Thyroid, nasopharynx, salivary glands, stomach, colon, bladder, lactating breasts

[edit] Pharmacokinetics

[edit] Excretion

Renal

[edit] Target organ

Thyroid, bladder, stomach, SI

[edit] Other

Therapeutic doses

  • Graves' (5-15 mCi)
  • Toxic nodule (20-30 mCi)
  • Primary cancer (30-100 mCi)
  • Mets (100-200 mCi)


Calculated therapeutic dose (mCi) = (gland weight x desired glandular dose [50-200 mCi/g]) / RAIU