Littoral cell angioma
 Discussion of Littoral cell angioma
- Littoral cell angioma of the spleen is a rare vascular tumor
- First described in 1991.
- Biologic behavior has not been firmly established.
- Littoral cell angiomas may occur at any age and have no gender predilection.
- Typically, patients with littoral cell angioma are found to have a splenic abnormality when they are being evaluated for laboratory evidence of anemia or thrombocytopenia.
- Splenomegaly is almost always present.
- An association between littoral cell angioma and other malignancies, including colorectal, renal, and pancreatic adenocarcinoma and meningioma, has been described.
- In most patients, because symptomatic hematologic problems are present and because the imaging findings are nonspecific, splenectomy is typically performed for definitive evaluation and treatment.
 Imaging Findings for Littoral cell angioma
- Littoral cell angioma should be considered in the differential diagnosis of multiple splenic lesions in patients with evidence of hypersplenism.
- Sonograms, CT scans, and MR images usually demonstrate splenomegaly and multiple lesions of similar size and appearance.
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 References for Littoral cell angioma
- Robert M. Abbott, Angela D. Levy, Nadine S. Aguilera, Luis Gorospe, and William M. Thompson. From the Archives of the AFIP: Primary Vascular Neoplasms of the Spleen: Radiologic-Pathologic Correlation. RadioGraphics 2004 24: 1137-1163.