Malignant salivary gland neoplasms
 Discussion of Malignant salivary gland neoplasms
- The most common malignant neoplasms occurring in salivary glands are:
- Mucoepidermoid carcinoma
- Adenoid cystic carcinoma.
- Squamous cell carcinoma, acinic cell carcinoma, and adenocarcinoma are less common.
- Less than 30% of focal lesions in the parotid gland are malignant, whereas almost 50% of focal lesions in the submandibular gland are malignant.
- Malignant tumors may grow rapidly, may be tender or painful at palpation, may be fixed to the background, and may cause facial nerve paresis or paralysis.
- Mucoepidermoid carcinoma occurs mostly between 30 and 50 years of age.
- Mucoepidermoid carcinoma may show several levels of differentiation and thus different tendencies to infiltration, metastases, and progress
- Adenoid cystic carcinoma, which is a slowly growing tumor, shows a particular tendency to nerve infiltration and late metastases are frequent.
 Imaging Findings for Malignant salivary gland neoplasms
- US features of malignant salivary neoplasms include the following: an irregular shape, irregular borders, blurred margins, and a hypoechoic inhomogeneous structure.
- The internal structure of a malignant tumor at US may be not only solid but also cystic or cystic with a mural solid nodule.
- Malignant tumors may have a lobulated shape, similar to that of pleomorphic adenomas.
- MRI: as result of increased cellularity and decreased mucous production, high-grade malignancies tend to have low signal intensity with both T1- and T2-weighted sequences (benign and low-grade malignancies are bright on T2-weighted images}.
 See Also
 External Links
 References for Malignant salivary gland neoplasms
- Ewa J. Bialek, Wieslaw Jakubowski, Piotr Zajkowski, Kazimierz T. Szopinski, and Antoni Osmolski. US of the Major Salivary Glands: Anatomy and Spatial Relationships, Pathologic Conditions, and Pitfalls. RadioGraphics 2006 26: 745-763.