Discussion of May-Thurner syndrome
- May-Thurner syndrome is caused by compression of the left common iliac vein by the right common iliac artery.
- May-Thurner sydrome may lead to leg swelling, varicosities, deep vein thrombosis, chronic venous stasis ulcers, or more serious complications, such as pulmonary embolism.
- May-Thurner syndrome has been estimated to occur in 2%–5% of patients who undergo evaluation for lower extremity venous disorders,
- It is not known why the normal anatomic relationship between the left common iliac vein and right common iliac artery is disrupted and begins to interfere with venous flow.
- May-Thurner syndrome is a progressive disease with substantial long-term disabling complications.
- An aggressive approach designed to relieve the mechanical compression should be strongly considered.
 Imaging Findings for May-Thurner syndrome
- An iliac venogram remains the diagnostic test of choice
- Demonstrates the compression itself
- Pressure gradient measurement can be performed to confirm the hemodynamic significance of the compression.
- An additional and important diagnostic finding is the presence of tortuous venous collaterals crossing the pelvis to join contralateral veins.
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 References for May-Thurner syndrome
- Barbaros E. Cil, Erhan Akpinar, Musturay Karcaaltincaba, and Devrim Akinci. Case 76: May-Thurner Syndrome. Radiology 2004 233: 361-365