Discussion of Nephrogenic adenoma
- A nephrogenic adenoma is not a neoplastic mass but a benign reactive process that occurs in the urothelium.
- Chronic irritation by calculi, infection, injury, or previous surgery incites metaplasia of the urothelium, which develops growths.
- A typical case is a patient with a history of undergoing repeated biopsies for urothelial carcinoma, with the reparative process causing a nephrogenic adenoma.
- Irritative voiding symptoms or hematuria are the most common symptoms.
- Patient age ranges from 26 to 80 years
- Men are three times more likely than women to develop nephrogenic adenoma.
- At histologic analysis, the adenoma resembles immature urothelial or metanephric structures.
 Imaging Findings for Nephrogenic adenoma
- Imaging studies reveal polypoid or sessile masses within the bladder or irregular mucosa, all of which are nonspecific findings; the diagnosis can be made only with a histologic evaluation.
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 References for Nephrogenic adenoma
- Jade J. Wong-You–Cheong, Paula J. Woodward, Maria A. Manning, and Charles J. Davis. From the Archives of the AFIP: Inflammatory and Nonneoplastic Bladder Masses: Radiologic-Pathologic Correlation. RadioGraphics 2006 26: 1847-1868.