Discussion of Omphalocele
- Omphalocele and gastroschisis are the two most common major congenital abdominal wall defects.
- With omphalocele, the intraabdominal viscera herniate into the base of the umbilical cord and the herniated viscera are covered by the peritoneum and amnion.
- Incidence of omphalocele reported in the literature varies considerably, ranging from 0.8 to 3.9 cases per 10,000 births.
- Omphalocele is known to be a part of various anomaly syndromes, such as Beckwith-Wiedemann syndrome, pentalogy of Cantrell, and omphalocele exstrophy imperforate anus spinal defects syndrome.
- Associated structural anomalies have been noted in 27% to 91% of fetuses with omphalocele
- Abnormal chromosomes, mainly those of trisomy 13 and trisomy 18, have been observed in 20%–50% of cases.
 Imaging Findings for Omphalocele
- The sonographic diagnosis of an abdominal-wall defect can be made when a mass containing viscera is seen to project from the anterior abdominal wall of the fetus.
- Sonographic differentiation of omphalocele from gastroschisis has been based on the site of cord insertion, the presence of a covering membrane, and the type of viscera protruding into the defect.
 See Also
 External Links
 References for Omphalocele
- Bair, JH, Russ, PD, Pretorius, DH, Manchester, D, Manco-Johnson, ML. Fetal omphalocele and gastroschisis: a review of 24 cases. Am. J. Roentgenol. 1986 147: 1047-1051.
- Shraga Blazer, Etan Z. Zimmer, Ayala Gover, and Moshe Bronshtein. Fetal Omphalocele Detected Early in Pregnancy: Associated Anomalies and Outcomes. Radiology 2004 232: 191-195.