Osteoblastoma

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[edit] Discussion of Osteoblastoma

  • Osteoblastoma is a rare, benign primary tumor of bone accounting for approximately 1% of all primary bone tumors.
  • Histologic differentiation between osteoid osteoma and osteoblastoma can be very difficult, and in a considerable number of patients it can be impossible.
  • The most important criterion in equivocal cases is the size of the lesion. Osteoblastomas are usually larger than 2 cm due to the absence of limited growth potential, which is a feature of osteoid osteoma.


  • Osteoblastoma can occur in nearly every bone but is most commonly found in the spine.
  • The tumor is equally distributed over the cervical, thoracic, lumbar, and sacral segments.
  • Osteoblastoma in the vertebral column is most commonly a lytic lesion of bone, arising in the posterior elements with destruction of the cortex and expansion into the surrounding soft tissues.


  • The second most common location of osteoblastoma is in the long tubular bones.
  • The femur and tibia are most frequently involved.
  • In the long bones, osteoblastoma usually is seen as a round or oval lucent tumor with matrix minenalization arising proximally in the diaphysis.

[edit] Differential Diagnosis for Osteoblastoma

[edit] Imaging Findings for Osteoblastoma

[edit] Plain film

  • Osteoblastoma in the vertebral column is most commonly a lytic lesion of bone, arising in the posterior elements with destruction of the cortex and expansion into the surrounding soft tissues.
  • In the long bones, osteoblastoma usually is seen as a round or oval lucent tumor with matrix minenalization arising proximally in the diaphysis.

[edit] CT

  • Helps to further delinate plain film findings

[edit] Scintigrphy

  • Radionuclide bone scintigraphy invariably demonstrates an intense focal increase of activity and can be of great assistance in demonstrating and localizing disease specifically in the spine.


[edit] Images

Patient #1

[edit] See Also

[edit] External Links

[edit] References for Osteoblastoma