Rathke cleft cyst
 Discussion of Rathke cleft cyst
- Rathke cleft cysts are congenital nonneoplastic cysts arising from remnants of the embryonic Rathke cleft.
- They are common incidental intra- and/or suprasellar lesions.
- Forty percent are completely intrasellar, while 60% have some suprasellar extension
- Symptoms can occur from compression of the optic chiasm, hypothalamus, or pituitary gland.
 Differential Diagnosis of Rathke cleft cyst
 Imaging Findings for Rathke cleft cyst
- Imaging characteristics vary widely.
- Smoothly marginated cysts that vary in size from a few millimeters to 1–2 cm.
- Nonenhancing noncalcified intra- and/or suprasellar cyst with an intracystic nodule: small nonenhancing intracystic nodule is considered a virtually pathognomonic sign of a Rathke cleft cyst.
- Approximately half are hyperintense on T1-weighted images, while half are hypointense.
- On T2-weighted images, 70% are hyperintense and 30% are iso- or hypointense.
Patient #1: Contrast enhanced MR images demonstrate a Rathke cleft cyst
 See Also
 External Links
 References for Rathke cleft cyst
- Anne G. Osborn, and Michael T. Preece. Intracranial Cysts: Radiologic-Pathologic Correlation and Imaging Approach. Radiology 2006 239: 650-664.