Discussion of Sclerosing mesenteritis
- Sclerosing mesenteritis is a rare, idiopathic disorder characterized by tumorlike masses in the mesentery.
- Masses are composed of chronic, nonspecific inflammation, fat necrosis, and fibrosis.
- Sclerosing mesenteritis involves the small bowel mesentery in most cases (can also affect the colonic mesocolon).
- In the majority of cases, the mesentery becomes thickened and shortened.
- Fixation and kinking of the bowel may occur.
- The average age of patients at presentation for sclerosing mesenteritis is 60 years
- Condition occurs twice as often in men than women.
- Abdominal pain or a palpable abdominal mass is the most common clinical manifestation.
- Sclerosing mesenteritis has a favorable prognosis and may be self-limiting.
- Differential diagnosis:
- When sclerosing mesenteritis manifests as a spiculated mesenteric mass with or without calcification, the most important differential diagnosis is carcinoid metastatic to the mesentery.
- Metastatic disease from other primary neoplasms, lymphoma, and soft-tissue sarcomas should also be considered in the differential diagnosis.
- There are many synonyms for sclerosing mesenteritis including:
- Mesenteric panniculitis
- Retractile mesenteritis
- Mesenteric lipodystrophy
 Imaging Findings for Sclerosing mesenteritis
- In sclerosis mesenteritis, there will be tumorlike masses in the mesentery.
- Sclerosing mesenteritis affects the small bowel by retraction and shortening of the mesentery rather than by direct extension or invasion. The result of mesenteric retraction and shortening is kinking or fixation of the small bowel.
- Partial or complete obstruction of the small intestines may occur.
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 References for Sclerosing mesenteritis
- Angela D. Levy, Jordi Rimola, Anupamjit K. Mehrotra, and Leslie H. Sobin. From the Archives of the AFIP: Benign Fibrous Tumors and Tumorlike Lesions of the Mesentery: Radiologic-Pathologic Correlation. RadioGraphics 2006 26: 245-264.