Synovial chondromatosis

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[edit] Discussion of Synovial chondromatosis

[edit] Primary synovial chondromatosis

  • Primary synovial chondromatosis is a benign monoarticular disorder
  • Of unknown origin
  • Characterized by proliferation and metaplastic transformation of the synovium, with formation of multiple cartilaginous or osteocartilaginous nodules within the joints, bursae, or tendon sheaths.
  • The knee is the most commonly affected joint (involved in greater than 50% of cases), followed by the elbow, hip, and shoulder, although any other joint may be involved.


  • Patients usually present with pain, swelling, and limitation of motion, which often progress slowly for several years.
  • The age range of affected patients is wide, but most present in the 4th or 5th decade of life.
  • Men are affected two to four times more frequently than women.
  • Removal of the intraarticular bodies is the preferred treatment, although local recurrence is not uncommon.
  • At pathologic analysis, synovial chondromatosis consists of multiple nodules of hyaline cartilage attached to the synovium. These nodules may detach to form loose bodies.
  • Cartilaginous bodies may contain cartilage alone, cartilage and bone, or mature bone with fatty marrow.

[edit] Secondary chondromatosis

[edit] Imaging Findings for Synovial chondromatosis

[edit] Primary synovial chondromatosis

  • Depends on the stage of disease and on the extent of calcification or ossification of the cartilaginous nodules.
  • In its most distinctive appearance, multiple small, well-defined, juxtaarticular nodules of uniform size are observed.
  • Calcification is absent in approximately 25%–30% of patients.
  • In these cases, plain radiographs may be normal or may reveal a nonspecific soft-tissue mass surrounding the joint, widening of the joint space, erosions of adjacent bones, or early osteoarthritic changes.

[edit] Secondary chondromatosis

  • Intraarticular bodies tend to be larger, less numerous, and more varied in size than in primary synovial chondromatosis.
  • Secondary osteochondromatosis typically demonstrates associated and more prominent changes of the underlying degenerative disease of the joint.

[edit] Images

Patient #1: Right shoulder synovial chondromatosis

Patient #2: Apple core appearance in right hip synovial chondromatosis

Patient #3

[edit] See Also

[edit] External Links

[edit] References for Synovial chondromatosis